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1

Coagulation factor and protease pathways in thrombosis and cardiovascular disease

ten Cate, H., Hackeng, T. M., García de Frutos, P.

Journal:

Thrombosis and Haemostasis

Year:

2017

Language:

english

File:

PDF, 458 KB

english, 2017

2

Low-density lipoprotein and its effect on human blood platelets

I. A. M. Relou, C. M. Hackeng…

Journal:

Cellular and Molecular Life Sciences

Year:

2003

Language:

english

File:

PDF, 177 KB

english, 2003

3

From Phage Display to Dendrimer Display: Insights into Multivalent Binding

Bastings, Maartje M. C., Helms, Brett A., van Baal, Ingrid, Hackeng, Tilman M., Merkx, Maarten, Meijer, E. W.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 2.79 MB

english, 2011

4

The Effect of Vitamin D Supplementation on Vitamin D Status and Parathyroid Function in Elderly Subjects*

LIPS, P., WIERSINGA, A., VAN GINKEL, F. C., JONGEN, M. J. M., NETELENBOS, J. C., HACKENG, W. H. L., DELMAS, P. D., VAN DER VIJGH, W. J. F.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1988

Language:

english

File:

PDF, 898 KB

english, 1988

5

Population pharmacodynamic model for low molecular weight heparin nadroparin in morbidly obese and non-obese patients using anti-Xa levels as endpoint

Diepstraten, Jeroen, Janssen, Esther J. H., Hackeng, Christian M., van Dongen, Eric P. A., Wiezer, René J., van Ramshorst, Bert, Knibbe, Catherijne A. J.

Journal:

European Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 664 KB

english, 2015

6

Surgical and molecular pathology of pancreatic neoplasms

Hackeng, Wenzel M., Hruban, Ralph H., Offerhaus, G. Johan A., Brosens, Lodewijk A. A.

Journal:

Diagnostic Pathology

Year:

2016

Language:

english

File:

PDF, 2.15 MB

english, 2016

7

Regulation of coagulation by protein S

Castoldi, Elisabetta, Hackeng, Tilman M

Journal:

Current Opinion in Hematology

Year:

2008

Language:

english

File:

PDF, 315 KB

english, 2008

8

Morphology and genetics of pyloric gland adenomas in familial adenomatous polyposis

Hackeng, Wenzel M., Montgomery, Elizabeth A., Giardiello, Francis M., Singhi, Aatur D., Debeljak, Marija, Eshleman, James R., Vieth, Michael, Offerhaus, G. Johan A., Wood, Laura D., Brosens, Lodewijk

Journal:

Year:

2016

Language:

english

File:

PDF, 36.37 MB

english, 2016

9

Reduced vitamin K status as a potentially modifiable risk factor of severe COVID-19

Dofferhoff, Anton S M, Piscaer, Ianthe, Schurgers, Leon J, Visser, Margot P J, van den Ouweland, Jody M W, de Jong, Pim A, Gosens, Reinoud, Hackeng, Tilman M, van Daal, Henny, Lux, Petra, Maassen, Cec

Journal:

Clinical Infectious Diseases

Year:

2020

File:

PDF, 929 KB

2020

10

Chemical synthesis of human protein S thrombin-sensitive module and first epidermal growth factor module

Tilman M. Hackeng, Philip E. Dawson, Stephen B.H. Kent, John H. Griffin

Journal:

Year:

1998

Language:

english

File:

PDF, 171 KB

english, 1998

11

Multivalent Peptide and Protein Dendrimers Using Native Chemical Ligation

Ingrid van Baal, Hinke Malda, Silvia A. Synowsky, Joost L. J. van Dongen, Tilman M. Hackeng, Maarten Merkx, E. W. Meijer

Journal:

Angewandte Chemie

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

12

Nucleophilic Catalysis of Oxime Ligation

Anouk Dirksen, Tilman M. Hackeng, Philip E. Dawson

Journal:

Angewandte Chemie

Year:

2006

Language:

english

File:

PDF, 114 KB

english, 2006

13

Multivalent Peptide and Protein Dendrimers Using Native Chemical Ligation

Ingrid van Baal, Hinke Malda, Silvia A. Synowsky, Joost L. J. van Dongen, Tilman M. Hackeng, Maarten Merkx, E. W. Meijer

Journal:

Angewandte Chemie International Edition

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

14

Nucleophilic Catalysis of Oxime Ligation

Anouk Dirksen, Tilman M. Hackeng, Philip E. Dawson

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 115 KB

english, 2006

15

Nε-(thiaprolyl)-lysine as a handle for site-specific protein conjugation

Pieter Van de Vijver, Dennis Suylen, Anouk Dirksen, Philip E. Dawson, Tilman M. Hackeng

Journal:

Year:

2010

Language:

english

File:

PDF, 529 KB

english, 2010

16

Noncovalent Synthesis of Protein Dendrimers

Edith H. M. Lempens, Ingrid van Baal, Joost L. J. van Dongen, Tilman M. Hackeng, Maarten Merkx, E. W. Meijer

Journal:

Chemistry - A European Journal

Year:

2009

Language:

english

File:

PDF, 515 KB

english, 2009

17

Pharmacokinetics of contrast agents targeted to the tumor vasculature in molecular magnetic resonance imaging

Marlies Oostendorp, Kim Douma, Tilman M. Hackeng, Marc A. M. J. van Zandvoort, Mark J. Post, Walter H. Backes

Journal:

Contrast Media & Molecular Imaging

Year:

2010

Language:

english

File:

PDF, 400 KB

english, 2010

18

Structure-function studies on human C4b-binding protein using monoclonal antibodies

Martin Hessing, Harry F. G. Heijnen, Tilman M. Hackeng, Jan J. Sixma, Bonno N. Bouma

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 1.02 MB

english, 1991

19

Solid-Phase Synthesis of a Cyclic NGR-Functionalized GdIIIDTPA Complex

Sander Langereis, Anouk Dirksen, Bas F. M. De Waal, Marcel H. P. Van Genderen, Quido G. De Lussanet, Tilman M. Hackeng, E. W. Meijer

Journal:

European Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 152 KB

english, 2005

20

Gadolinium-labeled quantum dots for molecular magnetic resonance imaging: R1 versus R2 mapping

Marlies Oostendorp, Kim Douma, Tilman M. Hackeng, Mark J. Post, Marc A. M. J. van Zandvoort, Walter H. Backes

Journal:

Magnetic Resonance in Medicine

Year:

2010

Language:

english

File:

PDF, 552 KB

english, 2010

21

Disparity Between In Vivo Zirconium-89-Labeled Cetuximab Uptake and EGFR Expression

H.J.W.L. Aerts, L. Dubois, T.M. Hackeng, P. Vermaelen, D. De Ruysscher, G. Lammering, G.A.M.S. van Dongen, B.G. Wouters, P. Lambin

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2007

Language:

english

File:

PDF, 43 KB

english, 2007

22

Biochemical markers of growth hormone (GH) sensitivity in children with idiopathic short stature: individual capacity of IGF-I generation after high-dose GH treatment determines the growth response to GH

G. A. Kamp, A. H. Zwinderman, J. Van Doorn, W. Hackeng, M. Frölich, E. Schönau, J. M. Wit

Journal:

Clinical Endocrinology

Year:

2002

Language:

english

File:

PDF, 313 KB

english, 2002

23

On the structure of phycaron

W. H. L. Hackeng, H. Copier, C. A. Salemink

Journal:

Recueil des Travaux Chimiques des Pays-Bas

Year:

1963

Language:

english

File:

PDF, 207 KB

english, 1963

24

Nanoparticles for Optical Molecular Imaging of Atherosclerosis

Kim Douma, Lenneke Prinzen, Dick W. Slaaf, Chris P. M. Reutelingsperger, Erik A. L. Biessen, Tilman M. Hackeng, Mark J. Post, Marc A. M. J. van Zandvoort

Journal:

Year:

2009

Language:

english

File:

PDF, 542 KB

english, 2009

25

Normocalcemia with persistent increase of parathyroid hormone: A prospective study

H. Mulder, W. H. J. Hackeng, J. Koster, H. Schaar

Journal:

Calcified Tissue International

Year:

1992

Language:

english

File:

PDF, 274 KB

english, 1992

26

Chronic overproduction of islet amyloid polypeptide/amylin in transgenic mice: lysosomal localization of human islet amyloid polypeptide and lack of marked hyperglycaemia or hyperinsulinaemia

J. W. M. Höppener, J. S. Verbeek, E. J. P. de Koning, C. Oosterwijk, K. L. van Hulst, H. J. Visser-Vernooy, F. M. A. Hofhuis, S. van Gaalen, M. J. H. Berends, W. H. L. Hackeng, H. S. Jansz, J. F. Morr

Journal:

Year:

1993

Language:

english

File:

PDF, 1.86 MB

english, 1993

27

Increased plasma calcitonin levels in young spontaneously hypertensive rats: role in disturbed phosphate homeostasis

R. J. M. Bindels, L. A. M. Broek, M. J. M. Jongen, W. H. L. Hackeng, C. W. G. M. Löwik, C. H. Os

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1987

Language:

english

File:

PDF, 812 KB

english, 1987

28

Twenty-four-hour plasma growth hormone (GH) profiles, urinary GH excretion, and plasma insulin-like growth factor-I and -II levels in prepubertal children with chronic renal insufficiency and severe growth retardation

A. C. S. Hokken-Koelega, W. H. L. Hackeng, T. Stijnen, J. M. Wit, S. M. P. F. Muinck Keizer-Schrama, S. L. S. Drop

Journal:

Pediatric Nephrology

Year:

1991

Language:

english

File:

PDF, 131 KB

english, 1991

29

Untersuchungen zur Parathyreoidea-Funktion bei chronisch hämodialysierten Patienten

R. Augustin, W. H. L. Hackeng

Journal:

Journal of Molecular Medicine

Year:

1977

File:

PDF, 608 KB

1977

30

Hyperparathyreoidismus (HPT) bei Dialysepatienten: Untersuchungen zum Regelkreis und Klassifikationsprobleme

R. Augustin, W. H. L. Hackeng

Journal:

Journal of Molecular Medicine

Year:

1981

File:

PDF, 952 KB

1981

31

Clinical use of a parathyroid hormone determination

S. A. Duursma, G. A. P. Indermaur, J. A. Raymakers, W. H. L. Hackeng

Journal:

Calcified Tissue International

Year:

1976

Language:

english

File:

PDF, 147 KB

english, 1976

32

The effect of age on the renal response to PTH infusion

M. A. B. Naafs, H. R. A. Fischer, G. Koorevaar, W. H. L. Hackeng, W. Schopman, J. Silberbusch

Journal:

Calcified Tissue International

Year:

1987

Language:

english

File:

PDF, 450 KB

english, 1987

33

Diminished effect of etidronate in vitamin D deficient osteopenic postmenopausal women

J. C. Koster, W. H. L. Hackeng, H. Mulder

Journal:

European Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 45 KB

english, 1996

34

Treatment of Pulmonary Embolism in an Extremely Obese Patient

Jeroen Diepstraten, Simone van Kralingen, Repke J. Snijder, Christian M. Hackeng, Bert van Ramshorst, Catherijne A. J. Knibbe

Journal:

Obesity Surgery

Year:

2009

Language:

english

File:

PDF, 97 KB

english, 2009

35

Characteristics of recombinant W501S mutated human γ-glutamyl carboxylase

B. A. M. Soute, D-Y. Jin, H. M. H. Spronk, V. P. Mutucumarana, P-J. Lin, T. M. Hackeng, D. W. Stafford, C. Vermeer

Journal:

Journal of Thrombosis and Haemostasis

Year:

2004

Language:

english

File:

PDF, 177 KB

english, 2004

36

Direct anticoagulant activity of protein S-C4b binding protein complex in Heerlen heterozygotes and normals

M. J. Heeb, R. R. Koenen, J. A. Fernández, T. M. Hackeng

Journal:

Journal of Thrombosis and Haemostasis

Year:

2004

Language:

english

File:

PDF, 217 KB

english, 2004

37

A head-to-head comparison between the VerifyNow® P2Y12 assay and light transmittance aggregometry for monitoring the individual platelet response to clopidogrel in patients undergoing elective percutaneous coronary intervention

J. W. VAN WERKUM, C. A. K. VAN DER STELT, T. H. SEESING, C. M. HACKENG, J. M. TEN BERG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2006

Language:

english

File:

PDF, 158 KB

english, 2006

38

Evaluation of the platelet response to clopidogrel with light transmittance aggregometry: peak aggregation or late aggregation?

J. W. VAN WERKUM, M. KLEIBEUKER, N. MIEREMET, J. M. TEN BERG, C. M. HACKENG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2007

Language:

english

File:

PDF, 174 KB

english, 2007

39

The flow cytometric VASP assay can be used to determine the effectiveness of clopidogrel in patients treated with abciximab

J. W. VAN WERKUM, C. A. K. VAN DER STELT, T. H. SEESING, J. M. TEN BERG, C. M. HACKENG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2007

Language:

english

File:

PDF, 137 KB

english, 2007

40

Post-translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification

L. J. SCHURGERS, H. M. H. SPRONK, J. N. SKEPPER, T. M. HACKENG, C. M. SHANAHAN, C. VERMEER, P. L. WEISSBERG, D. PROUDFOOT

Journal:

Journal of Thrombosis and Haemostasis

Year:

2007

Language:

english

File:

PDF, 502 KB

english, 2007

41

The importance of anticoagulant agents in measuring platelet aggregation in patients treated with clopidogrel and aspirin

H. J. BOUMAN, J. W. VAN WERKUM, C. M. HACKENG, F. W. A. VERHEUGT, J. M. TEN BERG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2008

Language:

english

File:

PDF, 166 KB

english, 2008

42

Collagen-mimetic peptides mediate flow-dependent thrombus formation by high- or low-affinity binding of integrin α2β1 and glycoprotein VI

I. C. A. MUNNIX, K. GILIO, P. R. M. SILJANDER, N. RAYNAL, M. A. H. FEIJGE, T. M. HACKENG, H. DECKMYN, P. A. SMETHURST, R. W. FARNDALE, J. W. M. HEEMSKERK

Journal:

Journal of Thrombosis and Haemostasis

Year:

2008

Language:

english

File:

PDF, 567 KB

english, 2008

43

Comparison between hirudin and citrate in monitoring the inhibitory effects of P2Y12 receptor antagonists with different platelet function tests

C. A. C. M. PITTENS, H. J. BOUMAN, J. W. VAN WERKUM, J. M. TEN BERG, C. M. HACKENG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

44

Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel

H. J. BOUMAN, E. PARLAK, J. W. VAN WERKUM, N. J. BREET, H. TEN CATE, C. M. HACKENG, J. M. TEN BERG, D. TAUBERT

Journal:

Journal of Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 252 KB

english, 2010

45

Hereditary and acquired protein S deficiencies are associated with low TFPI levels in plasma

E. CASTOLDI, P. SIMIONI, D. TORMENE, J. ROSING, T. M. HACKENG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 241 KB

english, 2010

46

Thrombin generation-based assays to measure the activity of the TFPI–protein S pathway in plasma from normal and protein S-deficient individuals

L. F. A. MAURISSEN, E. CASTOLDI, P. SIMIONI, J. ROSING, T. M. HACKENG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 518 KB

english, 2010

47

Do not adjust the platelet count in light transmittance aggregometry when predicting thrombotic events after percutaneous coronary intervention

N. J. BREET, J. W. VAN WERKUM, H. J. BOUMAN, J. C. KELDER, J. M. TEN BERG, C. M. HACKENG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 135 KB

english, 2010

48

High on-aspirin platelet reactivity as measured with aggregation-based, cyclooxygenase-1 inhibition sensitive platelet function tests is associated with the occurrence of atherothrombotic events

N. J. BREET, J. W. VAN WERKUM, H. J. BOUMAN, J. C. KELDER, J. M. TEN BERG, C. M. HACKENG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 197 KB

english, 2010

49

CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment

A. SARABI, B. K. KRAMP, M. DRECHSLER, T. M. HACKENG, O. SOEHNLEIN, C. WEBER, R. R. KOENEN, P. VON HUNDELSHAUSEN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 451 KB

english, 2011

50

A case–control study on platelet reactivity in patients with coronary stent thrombosis

H. J. BOUMAN, J. W. VAN WERKUM, N. J. BREET, H. TEN CATE, C. M. HACKENG, J. M. TEN BERG

Journal:

Journal of Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 261 KB

english, 2011

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